Neurulation: coordinating cell polarisation and lumen formation
نویسندگان
چکیده
منابع مشابه
Neurulation: coordinating cell polarisation and lumen formation.
Cell polarisation in development is a common and fundamental process underlying embryo patterning and morphogenesis, and has been extensively studied over the past years. Our current knowledge of cell polarisation in development is predominantly based on studies that have analysed polarisation of single cells, such as eggs, or cellular aggregates with a stable polarising interface, such as cult...
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The correct development of blood vessels is crucial for all aspects of tissue growth and physiology in vertebrates. The formation of an elaborate hierarchically branched network of endothelial tubes, through either angiogenesis or vasculogenesis, relies on a series of coordinated morphogenic events, but how individual endothelial cells adopt specific phenotypes and how they coordinate their beh...
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PURPOSE OF REVIEW The lumen of a blood vessel is essential for providing blood to any given tissue. Here, we discuss the molecular and cellular mechanisms underlying vascular lumen formation in invertebrates and vertebrates and highlight a new hypothesis describing oxygen transport in human malignant tumors. RECENT FINDINGS Several cellular mechanisms exist for blood vessel formation, that is...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2012
ISSN: 0261-4189,1460-2075
DOI: 10.1038/emboj.2012.325